The City of Phoenix does not have or issue a general business license. Only certain activities are regulated and require a license or require a recommendation/approval from the City.
If you will also be conducting business in any surrounding cities, please check with each of those individual cities on any rules, regulations or requirements to conduct business there.
For information about other City of Phoenix or State/County permits, licenses, or approvals, please refer to the bottom section of the License Services home page.